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KMID : 0363219960340020345
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Korean Journal of Dermatology
1996 Volume.34 No. 2 p.345 ~ p.349
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Transfusion-Associated Grafte-Versus-Host Disease in Patient with Pheumatoid Arthritis
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Abstract
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Graft-versus-host disease can develop in immunosuppressed individuals who receive blood product transfusions that contain immunocompetent lymphocytes. We report a case of transfusion-associated graft-versus-host disease(TA-GVHD) that developed in
a
patient with acute lymphocytic leukemia who were undergoing therapy. The groups at risk for development of TA-GVHD, the clinical presentation and course, and methods of diagnosis are summarized. Prevention of TA-GVHD is possible by irradiation of
blood
products given to patients at risk, but problems remain in determining the groups that warrant such measures. We should be aware of the risk of developing TA-GVHD after. Roatine blood transrusion, especially in areas where the population's HLA
types are
rather homogeneous. (Kor J Derdmatol 1996;34(1) : 345~349)
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